Contributing Authors | p. x |
Preface | p. xv |
Introduction--The History of Renal Immunopathology | p. 1 |
Process-Related Pathophysiology | p. 13 |
Normal Immune Responses | p. 15 |
Immunopathogenesis of Renal Diseases--An Overview | p. 47 |
Pathophysiology of Progressive Renal Disease | p. 55 |
Mechanisms of Renal Fibrogenesis | p. 73 |
The Immune Response and Renal Injury | p. 103 |
Induction of the Nephritogenic Immune Response | p. 105 |
Immunogenics of Renal Disease | p. 105 |
Immunologic Tolerance and the Induction of Autoimmunity | p. 139 |
Renal Expression of MHC Antigens | p. 171 |
Antigen Presentation by Renal Parenchyma: Protection or Promotion from Renal Injury | p. 195 |
Nephritogenic Antigens in the Cellular or Extracellular Membrane | p. 207 |
Mechanisms of Immune Injury | p. 225 |
Pathophysiology of Acute Immune Injury | p. 225 |
Development and Expression of Nephritogenic T Cells | p. 241 |
Molecular Structure and Expression of Nephritogenic Autoantibodies | p. 257 |
Mechanisms of Immune Complex Formation and Deposition in Renal Structures | p. 277 |
Apoptosis in Acute Renal Inflammation | p. 297 |
Mechanisms of Allograft Rejection | p. 321 |
Mediation of Immune Renal Injury | p. 345 |
Humoral Mediators of Immune Injury | p. 347 |
Glomerular Injury Due to Antibody Alone | p. 347 |
Complement and Complement Regulatory Proteins in Renal Disease | p. 367 |
Proteases and Oxidants in Glomerular Injury | p. 395 |
Growth Factors and Cytokines | p. 415 |
Endothelin and Nitric Oxide | p. 465 |
Eicosanoids | p. 489 |
Coagulation and Thrombosis in Immunologic Renal Diseases | p. 511 |
Cellular Mediators of Immune Injury | p. 521 |
Chemoattractants and Chemokines in Renal Disease | p. 521 |
Leukocyte Adhesion | p. 551 |
Neutrophils | p. 579 |
Platelets | p. 593 |
Macrophages in Immune Renal Injury | p. 609 |
The Formation of Glomerular Crescents | p. 633 |
Glomerular Mesangial Cells | p. 657 |
The Glomerular Podocyte | p. 693 |
Animal Models of Immunologic Renal Diseases | p. 709 |
Immune Models of Glomerular Injury | p. 711 |
Immune Models of Tubulointerstitial Injury | p. 779 |
Patient Evaluation and General Considerations | p. 815 |
Clinical Evaluation and Management of Hematuria and Proteinuria | p. 815 |
Morphologic Evaluation of Immune Renal Disease | p. 845 |
Interpretation of Clinical Studies of Renal Disease | p. 871 |
Primary Glomerular Diseases | p. 899 |
Postinfectious Glomerulonephritis | p. 899 |
Immunoglobulin A Nephropathy | p. 931 |
Anti-Glomerular Basement Membrane Disease | p. 949 |
Minimal-Change Nephrotic Syndrome | p. 969 |
Mesangioproliferative Disease | p. 987 |
Focal Segmental Glomerulosclerosis | p. 1001 |
Membranous Nephropathy | p. 1029 |
Secondary Glomerular Diseases | p. 1057 |
Systemic Lupus Erythematosus | p. 1057 |
Renal Vasculitis | p. 1105 |
Henoch-Schonlein Purpura | p. 1127 |
Idiopathic Membranoproliferative Glomerulonephritis | p. 1141 |
Amyloidosis, the Dysproteinemias, and Immunotactoid Glomerulopathy | p. 1155 |
Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura and Anti-Phospholipid Antibody Syndromes | p. 1173 |
Clinical and Immunopathogenic Aspects of Human Immunodeficiency Virus-Associated Renal Diseases | p. 1203 |
Recurrent and De Novo Glomerular Disease in Renal Transplants | p. 1225 |
Secondary Glomerulonephridities | p. 1247 |
Interstitial Nephritis | p. 1269 |
Acute Interstitial Nephritis | p. 1269 |
Subject Index | p. 1283 |
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